2379. Multicenter Evaluation of Ceftazidime–Avibactam for Multidrug-Resistant Gram-Negative Bacterial Infections
نویسندگان
چکیده
منابع مشابه
Colistin efficacy in the treatment of multidrug-resistant and extremelydrug-resistant gram-negative bacterial infections.
BACKGROUND/AIM Colistin is used as a salvage therapy for multidrug-resistant and extremely drug-resistant gram-negative bacterial infections. Our aim was to evaluate colistin efficiency and toxicity in the treatment of these resistant gram-negative bacterial infections. MATERIALS AND METHODS This is a retrospective study carried out in a tertiary care hospital during 2011-2013. Study data wer...
متن کاملColistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections.
The emergence of multidrug-resistant gram-negative bacteria and the lack of new antibiotics to combat them have led to the revival of polymyxins, an old class of cationic, cyclic polypeptide antibiotics. Polymyxin B and polymyxin E (colistin) are the 2 polymyxins used in clinical practice. Most of the reintroduction of polymyxins during the last few years is related to colistin. The polymyxins ...
متن کاملmultidrug resistant gram-negative bacilli in lower respiratory tract infections.
background: lower respiratory tract infections are among important causes of morbidity and mortality for all age groups. the emergence of multidrug resistant gram-negative bacilli is an issue of increasing concern. materials and methods: a retrospective study including respiratory specimens (sputum and bal) was conducted in our tertiary care centre. samples were processed for microscopy, cultur...
متن کاملTreatment of multidrug-resistant Gram-negative infections in children.
Antibiotic resistance in conjunction with the erosion of the drug development pipeline may lead us into a bleak future, a "post-antibiotic era." Because of a shortage of studies addressing treatment options for multidrug-resistant Gram-negative (MDRGN) infections in children, data must be extrapolated from the adult literature. However, even adult studies are limited by significant methodologic...
متن کاملColistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections.
Increasing multidrug resistance in Gram-negative bacteria, in particular Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, presents a critical problem. Limited therapeutic options have forced infectious disease clinicians and microbiologists to reappraise the clinical application of colistin, a polymyxin antibiotic discovered more than 50 years ago. We summarise recent...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2018
ISSN: 2328-8957
DOI: 10.1093/ofid/ofy210.2032